tech & ai
Rank 1. Anthropic signs $11.6 billion, seven-year computing deal with AkamaiSource bloomberg.com
Anthropic signed an $11.6 billion, seven-year contract with Akamai Technologies for computing power, Bloomberg reported on September 25, building on a previous $1.8 billion deal between the two companies. The new contract is entirely focused on CPUs. Bloomberg Intelligence analyst Mandeep Singh said the deal should boost Akamai's growth and that its profitability profile looks attractive given the contract structure.
Topics: infrastructure and cloudaicloudbusiness
Why it ranked: A seven-year, $11.6 billion CPU-focused contract between a frontier AI lab and a major CDN provider is one of the largest AI infrastructure commitments reported to date, with direct consequences for how AI compute is sourced and priced across the industry.
read source: Anthropic signs $11.6 billion, seven-year computing deal with Akamai
Rank 2. Microsoft launches Copilot app with Home, Code, and AutopilotSource theverge.com
The Verge reports Microsoft unveiled a redesigned Copilot app on September 25 that bundles chat, coding, and Autopilot agents into one interface, rebranding its Scout assistant as Autopilot. Home combines Chat and Cowork, Code lets workers build sandboxed internal apps with GitHub Copilot technology, and Autopilot runs as a cloud agent with its own tenant identity, memory, and workspace. Home and Code begin Frontier rollout in the coming weeks, with Autopilot entering private preview later in September.
Topics: AI and machine learningaiplatformsdeveloper toolsbusiness
Why it ranked: Usage-based billing for Autopilot and Code ties enterprise AI spend to long-running agent work rather than a flat seat license.
read source: Microsoft launches Copilot app with Home, Code, and Autopilot
Rank 3. Enveda raises $311M Series E at $2B for AI natural drugsSource techcrunch.com
TechCrunch reports Enveda raised a $311 million Series E led by Catalio Capital Management at a $2 billion valuation, doubling the figure from a year earlier. Founder Viswa Colluru’s company uses AI to find drug candidates in plants and microbes and is testing medicines for severe skin conditions and for maintaining weight loss after patients stop GLP-1 drugs. The round follows positive early clinical readouts and brings total capital raised above $845 million.
Topics: startups and businessaibusinessscienceplatforms
Why it ranked: The financing funds later-stage trials for AI-discovered oral drugs already in human testing for eczema, asthma, and post-GLP-1 weight maintenance.
read source: Enveda raises $311M Series E at $2B for AI natural drugs
Rank 4. Pilgrim raises $25M seed for Argus airborne biothreat sensorSource wsj.com
The Wall Street Journal reports Jake Adler’s Pilgrim raised a $25 million seed round at a $150 million valuation led by Buckley Ventures, with personal investments from Anthropic’s Logan Graham and Sholto Douglas. Pilgrim’s Argus is a roughly 50-pound device that samples air and runs genomic sequencing to flag airborne pathogens such as Ebola and anthrax. Kate Clark’s reporting says Anthropic leaders backed the startup amid concern that AI could enable new biological threats, and Pilgrim has begun early deployments tied to a CDC biosurveillance effort.
Topics: startups and businessaisecurityhardwarebusiness
Why it ranked: Frontier-lab researchers are personally funding hardware meant to detect airborne pathogens as AI biothreat fears rise.
read source: Pilgrim raises $25M seed for Argus airborne biothreat sensor
Rank 5. Microsoft launches major Copilot update with enterprise Autopilot agentSource cnbc.com
Microsoft announced its largest Copilot update on September 25, positioning the product as what it calls a "new OS for work" spanning every model, device, and task, according to CNBC. The update introduces Autopilot, a proactive long-running enterprise agent, along with new coding capabilities. CEO Satya Nadella said the motivation is to "diffuse rapidly accelerating intelligence everywhere."
Topics: AI and machine learningaibusinessdeveloper toolsplatforms
Why it ranked: Microsoft's repositioning of Copilot as a work operating system with long-running enterprise agents directly affects how businesses integrate AI into daily workflows across devices and software.
read source: Microsoft launches major Copilot update with enterprise Autopilot agent
Rank 6. Kalshi curtails AI people ads after race-swapping backlashSource businessinsider.com
Business Insider reports creator Elliot Choy accused Kalshi of copying his New York apartment-move video for an ad that replaced him with a white man. A Kalshi spokesperson said the ad was about four months old, made by an outside agency, that the company no longer uses AI-generated content depicting people, and that it is reviewing the agency relationship. Creator Pushpek Sidhu said he saw a similar race-swapped reuse of one of his videos earlier in 2026.
Topics: policy and societyaiculturepolicybusiness
Why it ranked: A major prediction-market advertiser is pulling AI depictions of people after creators say their videos were copied without consent.
read source: Kalshi curtails AI people ads after race-swapping backlash